A person who has two arseholes; usually caused by an untreated ab cyst of the anus.
Andy was a twopoo and he was able to fart in stereo.
by Jason Small May 24, 2007
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A person with two anus's. More commonly this is caused by an untreated anal cyst which breaks the skin and creates a second passage. There is another condition called genital duplication which is known to produce a second anus in sufferers.
A friend we once had apparently suffered from an anal cyst many years ago which created him a second anal passage.

Because we had no compassion for this person at all, we decided to call him twopoo - and so it was spoken, that from that day forward that anyone with the misfortune of having two arse holes would be known as a twopoo.

by Space Kat (=^.^=) June 6, 2007
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