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To use a public washroom inside of a high school, more precisely a catholic school. To pleasure yourself with the use of masturbation. The twazzle has only been spotted twice! Many users of the twazzle do not believe it is wrong.
When J.A.H had to really really do it! The twazzle takes place on the holyest of days.
Twazzle by Twizzle Twazzle November 24, 2006
word with no meaning. extremely fun to say when drunk/high...created out of randomness by my friend Tselar. you know you wanna say it.. go ahead. Twazzle.

also; Fo' Twazzle Muh Nazzle
Brandi When Drunk: ya know what?
Sean: what?
Brandi: Fo' Twazzle muh Nazzle.
Twazzle by Bittie July 15, 2006
A derivative of the word "Twat" that describes the pussy of a fat, over-sized women or a slut
Guy 1: "Dude check out Taylor"
Guy 2: "Dude are you high??? She has a fucking Twazzle!!
Guy 1: "Whoa... sorry, I missed her muffin-top"
Twazzle by SkyHigh10 March 11, 2011
An ongoing process of Twiticism. Pervasive idiocy. A situation of Moronitorium. Trump.
What a load of feckin’ twazzle!
Twazzle by NeuroGeek January 12, 2019

twazzle life 

A group of friends who gets saucy together
Look at them boyz sauced up them boyz twazzle life , aka direcktionz , banga and breeze
twazzle life by NanDaMan April 20, 2017

twazzle finger 

somebody who likes to finger twats/vaginas
hence the term
OR
they are a twazzle finger because their fingers smell of cum etc.

-extremly crude, i know.
"oh dude! *smells friends fingers* oh holy shizzz since when did you become a twazzle finger?!"
twazzle finger by .x.-Kiran_C-.x. January 24, 2008

twazzle nozzle 

When you pump cum into a coochie
I wanna perform a twazzle nozzle tonight
twazzle nozzle by Lacey-Kody March 20, 2006