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Use of methamphetamine/speed (T is slang for meth/speed). No speedbumps when t'd up=nothing to slow one down (bonus). Turnt/Turnt up is a synonym (the T once again referring to meth/speed).
I'm T'd up.
t'd up by DCRabbit June 12, 2018

t’d up 

Short for turnt up (high/drunk/excited)
Person 1: yo we’re getting t’d up tonight.
Person 2: boss shit
t’d up by Ambershit March 20, 2018

T’d up 

mane this basketball game betta b t’d up or imma have to dip
T’d up by kayristuhhh January 18, 2020

T’d up 

T’d up means Tightened up, not goofing off anymore, back on your defense / high alert; not being on no BS anymore. Getting back on demon timing
“I ain’t boutta get dunked on twice in a row, I’m T’d up now!”
“I might’ve got 0 kills the last few rounds, but trust I’m finna get T’d up next game.”
T’d up by YRG honeydip January 3, 2021

T’D up 

Ticked up /other words annoyed
T’D up by Sway_boy May 6, 2018

t’d up 

I t’d up, I had sex with a hoe.
t’d up by Hoebo May 5, 2018