2
1. A form of greeting
2. Bragging, trash talking. Like saying sup after you gain some advantage over the other person.
Person1: Sup wit it G?
Person2: Not much just ballin'

Person 3: SUP WIT IT
Person 4: Haha fuck that was a sick beatdown you gave that fake thug, man I wish I had been able to do that shit.

by MAKAVELI604 June 16, 2007
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