Short for Snakes on A Plane. A movie staring Samuel L. Jackson in which an assassin releases hundreds of snakes on a plane in order to kill a witness.
From the movie s.o.a.p:

"I've had it with these motherfucking snakes on this motherfucking plane!"
by Snorp March 29, 2006
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A chemical that when smoked gets you EXTREMELY fucked up.
Girl 1: Hey what happened last night.

Girl 2: I don't remember anything after I smoked that soap. It fucked me up.

Girl 1: it's not the only thing that fucked you.
by Annlyssa February 06, 2011
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Something you use to wash away filth.
My mom washed my mouth out with soap after i said the word "ass".
by CryBaby. September 06, 2015
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