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ringing somebodys doorbell, taking a ginormous dump on the step and running for your life whilst doing evil laughs ...
Bobby: What do you want to do tonight?
Jimmy: lets shit & run at marias house
Bobby: lets do it

later maria opens her door

Maria: ahhhh what the fuck is this thing ahhhhhh ... mmm tastes good...
by Abi and Katie July 04, 2008
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When you can't hold your shit in and you have to stop at a random building just to use the bathroom.
Guy #1: Dude, what took you so long?

Guy #2: Sorry I had to do a shit & run.
by Applesowce8572 December 23, 2016
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