To be in a dominating position where one has total or a
large share of control over an industry, business,
enterprise or most often a drug
spot.
1)
Chump: Yo look at that Escalade on 22s, that must be the cash
money millionaires
Lil Nigga: Nah that's poppi, he runs shit down on 25th son
2)
"You think this is a
joke motherfucker? I RUN
shit, not you. The game is MINE! (shoots competition in the face)"