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From the Card Captor Sakura English manga, "phwee" is the romanized version of the sound she makes ("Hoeeeeee..." {pronounced like ho-eeeee}). It's supposed to show surprise or confusion.
Tomoyo: Ah, spring! The time a man's fancy turns to love!
Sakura: Phwee?
by Yukita October 30, 2003
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A word used to show intense screeching anger or fear.
"Hey I just had sex with your girlfriend. Hope you don't mind."
"PHWEE!"
by EnigmaticCoffeeCup April 20, 2004
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