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open for business 

When a girl is on the pill meaning she can have sex.
Hey,there's sheila i heard shes on the pill so shes open for business.

Open for business 

When a female work colleague turns around, bends over her desk and drops her pants/panties to be taken from behind
Lady: come to my office, I’m open for business
Open for business by Figgyh December 10, 2018