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Anytime you do something that would be considered an extreme or ironic failure when sending any type of mail (i.e. email or letters). This can be augmented with the words epic and absolute.

just straight up fucking failing with anything involving mail or internet
When you are sending extremely private or revealing information via email and accidentally clicking the "reply all" button. then epically fail resulting in a mailure
mailure by krinky81 January 3, 2010
Related Words

[Fission Mailure] 

A word of which was founded when swapping the first letters of the phrase "Mission Failure"
1. A Complete Fail
2. The Act of Mailing A Fission
3. "WoW YoU F41L 50h4rd u n00b! Tr0l0l0l0l0l!!"
(Man is masturbating)Ohhh Babbyy hheerree iitt ccoommees!!! 'squirt' Whaaa????!!!! "FISSION MAILURE"

Man you real Mailed your Fission when you passed out at your wedding bro (ALL)"FISSION MAILURE!!!"
[Fission Mailure] by DatOneNigga February 14, 2012
the hilarious way people pronounce measure.
what is the maisure of angle 6?
maisure by hwatmaisure March 11, 2015
Maluree is a kind hearted female. She is always there to talk to and will listen. She is the most beautiful person in the world.
Maluree is the nicest person you will ever come across
maluree by 💅🏻 June 11, 2019
a complete try-hard, A Maclure always likes to think he is cool and he always thinks he's hot when he's not and he tries to flex his jawline but the truth is he doesn't have one. I feel bad for Maclure because they always think that. they are the best.
Omg Why are being A maclure
maclure by kjwefnjkse f November 23, 2021