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Expression used by craps dealers - you're trapped, no way out. could also mean:
your job is secure,
you're engaged to be married,
you knocked up your girlfriend & you're going to pay child support for the rest of your miseable life.
Pit Boss: Vinko is moving to Vegas so it looks like they'll promote Joey D.

Box Person: He's locked in like a come bet!
by the wetspot March 29, 2008
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