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The true meaning means Low Observable but many know it as the shit hole of the universe. Where, like in the movie Pirates of the Caribbean, you become part of the building because you work there so much. L.O. is part of the United States Air Force and is preformed on jets such as the B-2, F-117(retired),soon to come F-35 and the new F-22. The L.O. program usually has a 60 hour work week and easily goes over that. They work with hazerdous cancer causeing chemicals and best of all supervison that doesnt know what they're doing nor do they give a shit about there troops. Many talk about mutiny, mass homicide, and suicide. Most other career fields know about L.O. and know not to mess with them because of there ease of agitation.
I would tell you to go to hell (LO) but I work there and I dont want to see your ugly face everyday.

Another day in HELL.O.

F.T.P.

Welcome To The Suck!
L.O. by Another L.O. Degenerate December 17, 2008
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Pronounced El Oh, short for Loyalist a street in NF, can mean the street or the crew therein.
"what you doing today D$?"
"just chillin in/with the L.O."
l.o. by Dgal October 10, 2005
Related Words
Little One

Usually referring to a baby or toddler, or a young child.
I want to join the after party, but my L.O. needs to be tucked in by 9pm.
L.O. by Kitiwiti July 24, 2022
He's my L/O, my better half
She's my L/O aka my li'l Sis
L/O by BinksterUK February 11, 2012
An overused meme, also known as CADbortion and Loss.jpg, is a series of parodies based on a dramatic cartoon strip from the webcomic series Ctrl+Alt+Del in which the female lead suffers a miscarriage, which became a subject of widespread mockery among the readers. Lately, the lines I, II, II I_ represented the meme in a minimalist form.
Person 1: *shows the L O S S meme*
Person 2: Is... is this L O S S?
l o s s by evilK May 24, 2018

L.O.V.E.M.U.F.F.I.N.

The League Of Villainous Evildoers Maniacally United For Frightening Investments in Naughtiness (L.O.V.E.M.U.F.F.I.N.) is an organization dedicated to promoting evil.
L.O.V.E.M.U.F.F.I.N. is causing chaos again.
L.O.V.E.M.U.F.F.I.N. by MikefromAZ November 22, 2010

L.O.V.E. 

verb: The act of caring and giving to someone else...having someone's best interest and wellbeing as a priority in your life. To truly L.O.V.E. is a very selfless act.
Michael Jackson was a loving humaitarian and wanted to make the world a better place for all. He was the embodiment of L.O.V.E.
L.O.V.E. by PY Love and Peace November 2, 2012