herpaghonal syphilitis Share definition Flag The absolute WORST STD you can get. This is shit you get from a NASTY hoe! "Dude, stay away from her, she's got the herpaghonal syphilitis!" herpaghonal syphilitis by JeffJeffJeff March 17, 2006 0 0 Get merch Get the herpaghonal syphilitis mug. Buy Now — $32.95 See more merch