A Graphical User Interface. The addition of GUI's to most modern operating systems has revolutionised the populous' ability access pornographic material, and contributed greatly to the happiness of the single geek/male population.
by Axman6 January 25, 2008
 Get the guimug.
Get the guimug. by The Keasbey Knight April 19, 2008
 Get the guimug.
Get the guimug. by guiii August 17, 2006
 Get the guimug.
Get the guimug. by xxalaska101xx January 25, 2011
 Get the guimug.
Get the guimug. "What this goei?"
by Stefan Degeest May 18, 2003
 Get the guimug.
Get the guimug. a synonym for pussy,vagina, vaginal cavity, shit like that, can be used by anyone( but only sounds good in a black mans mouth). this version of the word was founded in technology class:
can also be a sub for bitch, broad, redbone, bobblehead, shit like that.
can also be a sub for bitch, broad, redbone, bobblehead, shit like that.
teacher: alright class GUI: what does it mean.
nigga: yo dats wat i got from ya momz:
other nigga: yea well ya ass better be happy dat ya moms GUI is nasty ass hell,
nigga: yo dats wat i got from ya momz:
other nigga: yea well ya ass better be happy dat ya moms GUI is nasty ass hell,
by yung chizzle June 13, 2007
 Get the guimug.
Get the guimug. by Bhursty1180 August 22, 2011
 Get the a guy's guymug.
Get the a guy's guymug.