Gui 

A mythological creature, often useless and bad at everything it does.

Man, you're such a gui ...

Gui by Nubita June 29, 2016

GUI 

Graphical User Interface.

A visual display of files, programs, and program directories designed to make it easier for a person to use a computer.

Microsoft Windows has an easy-to use GUI.

GUI by AYB April 4, 2003

gui 

A Graphical User Interface. The addition of GUI's to most modern operating systems has revolutionised the populous' ability access pornographic material, and contributed greatly to the happiness of the single geek/male population.

Oh dude, this pussy looks so hot in HD, thanks to my GUI!

gui by Axman6 January 25, 2008

GUI 

Stands for "Genius Under the Influence". It is a term used for individuals who come up with fantastic ideas when abusing some kind of substance, or for those students who actually do quality schoolwork while completely fucked up.

Student # 1: "I can't believe I got an 'A' on that paper. I was so high when I did it I couldn't even remember what I wrote about."

Student # 2: "WTF. You should totally be charged with a GUI."

GUI by GreenParrot713 October 26, 2009

GUI 

pronounced as Jooey: Sometimes you just cant decide wether you'd rather play some good old fashioned COD or get a nice blow from your girlfriend. Why not settle for both. This is where the GUI come in... Gaming under the influence. Now you can play with both sticks at the same time.

This the ultimate gaming experience. So get your girl, get your XBox and get under the influence.

Tommy was ignoring his girlfriend Laura, being he was in the middle of level 27 on Nazi Zombies. In order to resolve this conflict Laura proposed a GUI, which allowed him to keep his tip wet and destroy some zombies all at the same time.

GUI by Lulu&AmDam October 26, 2010

gui 

A way for total n00bs to use a computer.

Jim: The Mac OS X gui is cool!!!!

Tim: You're a n00b!

gui by The Keasbey Knight April 19, 2008

GUI 

The noise you make when something enters your asshole

Bill: GUI, GUI, GUI, yea, shove that loaf of bread in my asshole more Steve
Steve: Ok Bill. Your turn.
Bill: alrighty:
Steve: GUI GUI GU- OUCH! That really hurt bill

GUI by GUIMACHINE123 September 16, 2013