(a) more fucked up
(b) a person who is strange looking above the waist
(a) today was more fucked upper than yesterday.

(b) that chick sure is fucked upper
by Beeyobee December 30, 2004
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A combination of tobacco and marijuana smoked in the same pipe.
Hey, let's head down to the river and smoke some fuck-your-shit-uppers!
by CharlesJF July 26, 2011
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