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Fuck My Wife 

A phrase said in a similar manner and context to "Fuck My Life" except used when ones wife/girlfriend is the source of grief
Bill: Hey Mike I got some tickets to the Rangers game tonight, you in?
Mike: Oh hell yeah buddy, just let me run it by my old lady
Wife: Michael you promised me that you would watch the third Harry Potter movie with me tonight, you know how scared I get
Mike: ugh Fuck My Wife, sorry Bill I can't come
Fuck My Wife by Kim4321 March 31, 2010
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fuck my wife 

an exclaimation of frustration or horror.
fuck my wife by CHELApants December 9, 2007