a person who talks a lot of shit and usually is stuck on themselves who believes and follows their own b.s. straight up they ass.
look at how nichole is so stuck on herself she thinks her shit don't stink what an ass me hole..
by MJ Boa October 12, 2017
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The ultimate sarcastic phrase with a southern twist. Often referred to as " My Ass" and can be willingly interchanged .Commonly used in the south where in the instant they're trying to bait you into stating your opinion on something which also happens to be wrong.
Ex':

P2: who do you think has the best defense in the NFL
P1: The Eagles have the best defense in the league
P2(non usage): Best defense my ass!!
P2(usage): have the best defense me Ass
by DIMKI September 29, 2015
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Assume and you think you know what somebody wants or needs, you’ll be wrong
When you ASSUME (ass u me) you make a ‘ass’ out of ‘u’ and ‘me’
by Ramin99 September 22, 2018
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A response to someone who likes to insult or belittle you once there is a crowd to entertain. Usually it is the social arsonist that is the antagonist and this is a perfect, appropriate response.
ANTAGONIST -"What have you been doing all day? Walking around doing nothing? Have you fixed anything? "

RESPONSE - "Don't wipe your ass with me!"
by Horse head April 18, 2017
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When Scotsman & Scotswoman get horny they say a lot of things to do with ass for example "Put that cannonball right up me ass" As a Scotswoman loves that kind of stuff they say a thing like "fuck me ass". This can also be used as a sign that two are dating. Scotsmen will wear shirts that say "fuck me ass" on them
Scotsman: So ye want to get in me bed

Scotswoman: Sure!
Scotsman: So what do ye want?
Scotswoman: "Fuck me ass"

Dating

Scotswoman
by soupguy21 May 2, 2017
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A girl who puts down all other girls to make herself look better.
Mediocre Girl: “Hayley is so ugly

Boy: wow “‘Mediocre girl’ is such a pick me ass hoe”
by Ronnie_131 May 16, 2018
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