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Whatisitis 

A life threatening disease that can be contracted through excessive existential questioning. Some symptoms may include depression, substance abuse, social withdrawal, identity crisis, and a shitload of other dysfunctions. Although deadly, this disease can be cured with a large dose of distraction, available in both physical and mental forms.

Please note that even after a person has recovered from Whatisitis, it will never leave the body of the carrier. It is, however, non-hereditary. You can also attempt to spare your children the uncertainty of life by introducing them to extra-curricular activities and/or by brainwashing them.
You: What is that? *squinting*
Me: What is what?
You: What is THAT? *points to object in distance*
Me: What is WHAT? *using air quotes*
You: No, I'm serious.
Me: What is serious?
You: Ugh.
Me: What is ugh?
You: *thinks harder* Holy shit my brain is on fire... stop.
Me: What is stop?
You: *catching on now* What is is?
Me: What is what?
You: What is what is?
Me: Damn, I don't know what anything is anymore.
You: Me neither.
Me: Sorry for giving you Whatisitis. Then again, why am I speaking? Nothing makes sense! What is speaking and what is sense?!
You: Wanna smoke up?
Me: What does that mean? Oh fuck it, where's my bong?
Whatisitis by strawberryweedles April 12, 2010
Related Words

Wikilitis 

(n) The disease of loving wiki's so much that every idea or thought must go in to a wiki.
Hey man, what is Walter doing?

He came up with a new idea and is making an entry in that Wiki again.

Man! That guy has wikilitis!

wikiwikipediaencyclopediawikibrainnoob zombies
Wikilitis by PDFLover June 10, 2010

whiteitis 

an attraction to white people, mostly white men, but also applies to an attraction to white women and gender non conforming white people.

whiteitis can only being contracted by non-white people
“damn henry is so cute
“that white boy?”
“yeah…”
“damn boy, you got that whiteitis badddd”
whiteitis by olivegardenhousesalad January 16, 2022