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A infectious disease contracted by young american males or females through the popular culture of anime (Japanese Cartoons) and develop a heavy addiction to this culture at different stages.

Stage 1 (Low Addiction): Often talks about anime shows and characters

Stage 2 (Medium Low Addiction): Constantly talks about anime shows and begins to do impressions
Stage 3 (Medium Addiction): Begins to purchase anime posters and figurines

Stage 4 (Medium High Addiction): Purchases Japanese weapons such as Katanas and Anime Character Costumes and goes to every available Anime convention
Stage 5 (High Addiction): THIS IS THE POINT OF NO RETURN IF A PATIENT IS IN STAGE 5 THERE IS NO CURE FOR HIM. In Stage 5 the patient's love (key word) for anime has gone to a extreme level. The patient has purchased for him/herself a membership at Rosetta Stone just to learn a shitty version of Japanese and now starts to gain weight.

Stage 6 (Extreme Addiction): The patient shows an unhealthy obsession towards certain characters after the purchase of a body pillow (a pillow the size of that character or person) and begins to show sexual feelings toward the pillow.
As a professor in weebotology, I have never seen anything past stage 6 but I have seen some people on stage 6 where he/she could not be fixed. The only solution that I could come up with is bleach and I recommend clorox. Clorox is the only solution for weebola patients past stage 5.
Hey what happened to Jimmy? He was infected with Stage 6 Weebola. (proceeds to break down into tears)
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Like racism but against people who are weebs, that is, watch anime and enjoy the anime manga culture
Weeb: My teacher is such a weebist, whenever I watch hentai in class he gets angry
Weebist by eraj August 23, 2016
Related Words

weebshit 

An absolute disgraceful Instagram anime meme account ran by an awful weeb who does nothing but posts relatable animemes all-day. The only good thing about his existence & his page is that he's ad-free.
Guy 1: Do you follow @weebshit on Instagram?

Guy 2: Yes, I do.

Guy 1: I always knew you were a big fucking weeb
weebshit by Everyone's Waifu February 28, 2020

Webosphere

All things Web 2.0/social media -- that is: Twitterville, bloggerville, Google apps, Google docs, Google reader, Google groups, online communities/discussion boards/forums, LinkedIn, Facebook,Brazen Careerist and all other social networking sites all lumped into one huge World Wide Webosphere.
Social Media Weekend was two days of keynote speakers and panel discussions featuring some of the city's finest in The Webosphere. Find other examples here: jannamarlies.blogspot.com.
Webosphere by Just Janna November 19, 2009
combination of weeb and Jesus. an individual who is an anime fan, so kinda annoying, and kinda cool, hence jesus
you're such a weebus
weebus by w33b17 May 10, 2020
A Minecraft streamer with a MASSIVE DUMPY
I heard WeeBop couldn’t fit through a doorway because of his MEATY behind
WeeBop by JFK in DaBaby Car May 29, 2021
An overly zealous anime fan, usually a newer or younger fan to anime who is very loud and excited about anime. These fans are the loud minority of fans that are very upfront and loud about anime in public - unlike the silent majority of anime fans.

Weeboo is also associated with the idea with the idea that this anime fan is excited about anime, but does not know much about anime. This goes back to the generalization that weeboos are newer or younger fans.

These anime fans are the "stereotype" of anime fans which the general public points to as fans of anime. They are the type of anime fans that use Japanese in there everyday conversation or push there love of anime on other people who are outside the anime fandom. These people do not always understand the concept of inside voices.

They are also different from anime fans - or otakus in Western culture - who are zealous about their fandom in private or at appropriate times, such as anime conventions or with other anime fans.
Look at this weeboo running around screaming about Pokemon.

I was just talking to this weeboo who said they love Sailor Moon but couldn't name any of the Outer Senshi.

These weeboos make it look like every anime fan is a hyper screaming five year old.
weeboo by DuckyC December 9, 2012