Tweakballs Share definition Flag Being high on meth and not being able to concentrate on small tasks but still being able to correct your friend and talk shit. You need to put those tweakballs away. I've had enough corrections. Tweakballs by Phluffhead247 March 14, 2021 0 0 Get merch Get the Tweakballs mug. Buy Now — $32.95 See more merch