1.A phrase spoken in sarcastic response to an exclamation or question that could claim no basis in the conversation at hand. 2. A sarcastic phrase spoken in response to a statement made in regards to nothing and usually not following any discernible thought pattern.

This phrase is generally thought to refer to a person "George" who is slow or dim witted and is therefore continually dismissed with a "Thank you" for his worthless contribution. The phrase also carries undertones of an allusion to the work Of Mice and Men which, though George in this case is the smarter of the two, conjures up images of severe learning disability or mental retardation. In any event, the phrase is meant to imply that the person is below average intelligence and what they said is to be dismissed or explained in further detail depending upon the tone with which it was spoken.
1.
John: I think the Beatles are the greatest band of all time.
Joe: I think they could have benefited from a more improvisational influence.
John: An improvisational influence? They had a revolutionary sound and needed no further improvement. Making the Beatles a Jam Band would have ruined everything.
James: Did you guys ever notice that cotton candy is dry, but still sticky?
(Joe and John exchange a glance)
Joe: Thanks George...

2.
(John and James are riding in a car silently and have been so for some time)
James: You know, I really like the smell of basketballs.
John: Thanks George...you moron.
by thelongdickofthelaw March 18, 2008
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A sarcastic thank you to someone who has wronged you. The expression dates to an early 2000's Star Wars related "Thank You George" campaign was started on the internet and quickly spread through science fiction fandom. The campaign centered around a web site that sold "Thank You George" t-shirts and merchandise. The web site turned out to be registered to a game company called Decipher, who had produced a highly successful Star Wars collectible card game between 1995 and 2001, only to have Lucasfilm pull the license in favor of Hasbro toys, who produced a new card game that failed. The campaign seemed to have been started by Decipher as a way to profit from Star Wars without having to pay licensing, and a way to give George Lucas a sarcastic "thank you" after he killed Decipher's product in favor of Hasbro's product that failed.
Still no original editions on Blu-Ray. Thank You George!
by Doc Von Thorp September 7, 2020
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This is a day where we are thankful for georgenotfound and his amazing content and merch he provides. (georgenotfound.shop)
Did you hear today is Thankful for George Day? Everyone is so thankful for him.
by Anonymous Trump Supporter November 25, 2021
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