Tetrizini Handshake Share definition Flag The act of rubbing one's testicles on anothers in a handshaking manner. dude, that guy is so gay. i bet he loves tetrizini handshakes. Tetrizini Handshake by -AMAYBEXX- March 16, 2011 0 0 Get merch Get the Tetrizini Handshake mug. Buy Now — $32.95 See more merch