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Single Syndrome 

An unreasonable philosophy usually developed through puberty in adolescent males, that one may never be truly happy with their lives without a significant other.

This tends to manifest faster and more severely in those who have been rejected by a romantic interest a significant amount of times, and those who find themselves isolated in an environment where “everyone else” seems to have a partner.

This syndrome hammers in the absolute “need” for an s/o, so much that the subject finds it even more difficult to, ahem, *obtain* one, due to its side effects of obsessive behavioral patterns.

Usually the subject may grow out of this philosophy and focus on bettering themselves rather than just getting a date with someone. But if it doesn’t, usually because of the neglect of a friend or family member to address it, this syndrome germinates into a sense of entitlement to an s/o, morphing the subject into a Nice Guy.
A: Life sucks, man. If only I had a girlfriend.
B: Dude, stop acting like you need one.
A: But I do!
B: No you don’t, man. Seems like you’ve got a bad case of Single Syndrome
Single Syndrome by izzthekid February 27, 2022
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Single Syndrome 

The urge to flirt, fuck, or catch feelings for anyone become unbearably strong in the period right after leaving a relationship
“I wanna f••k him”
“Didn’t you just get out of a relationship? He’s mid ugly too, the single syndrome is real.”
Single Syndrome by cardboardbeach September 27, 2023

Single Mom Syndrome (SMS) 

When a single mother begins to dwell on being alone for the rest of their life and starts paying more attention to men than their children.
Child: Ugh! Mom is so obsessed with her new boyfriend it's like I don't even exist anymore, and when I do, everything is still about him! It's driving me crazy!

Dad: -sigh- She's just dealing with Single Mom Syndrome (SMS) right now. She'll get over it soon.

Single Mother Syndrome 

When a woman has been single and raising a family alone for a long time that they forget how to be co-dependent in a relationship.
In relationships she still suffered from single mother syndrome and couldn't relinquish control.
Single Mother Syndrome by 1erin2many February 25, 2015

Single Pringle Syndrome 

Single Pringle Syndrome is when you’re single but your single-ness is causing you sadness whenever you realize you’re alone without a significant other
Guy 1: Aw man, today’s Valentines Day. Single Pringle syndrome is hitting me hard.

Guy 2:… What the fuck is single Pringle syndrome?

Guy 1: tl;dr Im sad that im single

Guy 2: Makes sense

single emoticon response syndrome 

when her reply to anything you said is a single emoticon. in most cases the same one again and again.
you - blah blah blah blah blahblahblah blah blah blah blahblahblah blahblah blah blah blah blah blah

your crush - :D

you know that girl i like. i'd diagnose her with single emoticon response syndrome

Siegle Syndrome 

The feeling of pure infatuation with someone that you barely know. Occasionally leads to liking that someone's friend?
Pantea: "Remember that kid from ASB Camp? I've been texting him for such a long time..."
Cara: "Oh god... don't tell me it's the Siegle Syndrome"
Siegle Syndrome by HBLOVAAA December 13, 2010