Shits n' Giggles Share definition Flag To laugh in such a manner that you soil yourself. So, Niko kept making shits n' giggles and Brandon ran to the restroom. Shits n' Giggles by Niko Zorich December 28, 2009 0 0 Get merch Get the Shits n' Giggles mug. Buy Now ā $32.95 See more merch