1. A place which is far away from any place which is deemed to be inhabitable by the human species.
2. AKA "Dawson's Creek"
3. A place you can be when you find yourself in a troublesome position..usually floating without the aid of a paddle
"Oh man, I can't believe I lost my paperwork; that stuff took me hours and it needs to be in by tomorrow!"
"Sounds like you're up shit creek without a paddle, mate."