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To ignore or annoy someone by answering with the word. This word is famous for the long phrase and has no point to it. The best time to use this is when you do not know what a girl is talking about, when a guy is talking so much shit and you don't feel like saying much back, when you want to confuse the person, and when you want to ignore the person.
"You are annoying."
"Saaaaaaaaaaaaaaaaammmmeeeee "
"What?"
"Saaaaaaaaaaaaaaaaammmmeeeee"

"The presentation is on bullying."
"Saaaaaaaaaaaaaaaaammmmeeeee "

You autistic as fuck, shut the fuck up, kys!
"Saaaaaaaaaaaaaaaaammmmeeeee"

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