Skip to main content

SUPOLOPOLOPISIS

1. A disease which infects the brain directly, resulting in a deadly combination of insanity and brain cancer.
Person 1: DUDE I HAVE SUPOLOPOLOPISIS
Person 2: LOL pwned
by super-mega irishman December 8, 2006
mugGet the SUPOLOPOLOPISIS mug.

Share this definition

Sign in to vote

We'll email you a link to sign in instantly.

Or

Check your email

We sent a link to

Open your email