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no-scope 

When the male achieves penetration without the assistance of his or his partners hands.
boy: "OMG I just no-scoped your vag LOL!!"
girl: "WTF hax..."
no-scope by Nemex January 10, 2008

No-Scope 

verb or noun: A Halo and Halo 2 term used on Xbox Live. A true no-scope is a headshot with the sniper rifle without using any zoom at all. A common form of pwnage. No-scopes are often in Halo montages. Rarely a player can get a "double" no-scope: two no-scopes one after the other resulting in a double kill.
No-scope followed by teabag:
"NO-SCOPE!!! That's right, son, I don't even have to aim and I pwn you. OooooH Yeeaah! How do my balls taste?"
No-Scope by KillerOrange May 11, 2006

no-scope 

Taking a shit with the lights off - an extremely risky and difficult manouver. Many factors must be taken into consideration when attempting a no-scope: overestimation of bowl circumference and neglect of splashback are frequently encountered obstacles.
dude: ahhhhh i just pulled off a sick no-scope in your bathroom

man: motherfucker you better not have clipped the seat
no-scope by wangmagnet December 14, 2010

No-Scope 

The act of pinching the tip of ones penis before ejaculation and then releasing, thus creating a powerful projectile of semen and targeted torward a femals eye, once landed, the man shouts "no-scope!"
Veater said he no-scoped Chelsea from 10 feet!
No-Scope by The Big Ezzie January 11, 2011

no scope 

Generally speaking, the act of killing someone in a first person shooter game with a one shot gun (sniper rifle, bolt action rifle, etc) without using a telescopic sight or sniper scope. Most commonly, the term is used to mean that you fired such a gun from the hip and killed someone with it, however it can also (debatably) mean that you pulled up iron sights on a sniper rifle / bolt action rifle and then killed someone that way. The term does not apply to shotguns, semi-automatic rifles (unless they can be scoped), or any automatic weapon.

No scoping is generally viewed as an act of skill (or luck, depending on who you talk to and the mechanics of the game you're playing). This is because you are killing someone with one shot through a (usually) large crosshair and also risk exposing yourself if you miss. However, the amount of prestige that is attached to a single no scope depends on the distance and rate of success; i.e. if you no scope once and do this by killing a guy who you are literally next to, that doesn't take much skill, but if you continually no scope guys who are halfway across the map, that's some seriously good shit on your behalf. On a related note, no scope headshots get you some serious prestige if you can pull them off constantly.
Example (in COD5):

Player 1: Damn, I just no scoped some guy on
no scope by LPB-2009 March 28, 2009

no scope 

The act of not scoping to kill an opponent.
Commonly used in Halo with a sniper but not limited to.

No scoping is NOT applicable to weapons where scoping is not required. ex. ak47, m4a1, battle rifle, SMG, etc.
Blue guy 1: No scope headshot!
Blue guy 2: Nice!
Dead guy: I just got owned..
no scope by JcThPS January 10, 2007