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Mindfucked 

To have your mind totally fucked by a woman to the point of mental suicide.
Whoa dude, Savannah just totally mindfucked me last night. I'm going to go blow my brains on the wall. ttyl man.

Hey man, guess what happened last night? I got totally mindfucked by Savannah. She is such a total mindfuck.
Mindfucked by Selby7390 January 14, 2009

MindFucked 

A term that rose to popularity after PDiddy said in the spring 2010 movie "Get him to the greek". Herds of sheep then began to say it to describe the summer 2010 movie "Inception".
PDiddy: "I'm mindfucking you right now"
Jonah Hill: "I hope you're wearing a condom because I have a dirty mind"

Random Guy/Sheep: "Dude, Inception was such a mindfuck!"
YOU: " I KNOW IVE READ 30 FACEBOOK STATUS'S SAYING I GOT MINDFUCKED"
MindFucked by realdanger July 23, 2010

mindfucked 

The feeling you get after you finished watching Breaking Dawn Part 2
Buboy: "Holy shit, did you watch Breaking Dawn yet?"

Krosna: "Yeah bro, I was totally mindfucked
mindfucked by #krosna November 25, 2012

Mindfucked 

When your mind is completely shocked and blown away by some kind of truth exposed to it, an epiphany that you don't recover from, being undone
Man she got mindfucked when God revealed how real he was to her.

Operation Mindfuck 

Often called simply OM, Operation Mindfuck was popularlized in "The Illuminatus! Trilogy" by Robert Shea and Robert Anton Wilson. It involves challenging people's perspectives, and shaking them out of their reality tunnels by unexpected actions and events. These usually involve strange twists on normalcy.

Many OMs involve subtlety, so that those whose reality perspective is being challenged don't know whether something's being pulled on them or not. Thus Operation Mindfuck often involves a degree of paranoia.

Operation Mindfuck was created in the 1960s by Ho Chi Zen (aka Lord Omar Khayyam Ravenhurst or Kerry Thornley, co-founder of Discordianism) with fellow Discordians Malaclypse the Younger, The GameMaster of Florin, Dr. Mordecai Malignatus, Harold Lord Randomfactor, and others.

OMs may be performed solo, by a few people, or by a large group. Operation Mindfuck often involves random elements, using the game theory concept that "the only strategy an opponent cannot predict is a random strategy." Participants may use random elements to make decisions, such as rolling dice.

OMs are often done by unconnnected groups of small cells of people, similar to the military tactics of Mao Tse-tung. A participant may know who's in one cell, but have no idea who else is involved in other cells. This makes it extremely difficult to pinpoint and stop those involved.

In the 21st century, OMGASM, or Operation Mindfuck: Golden Apple Seed Mission, was begun by Professor Cramulus and others. In an OMGASM, people spread the word about a coming OM so it can grow everywhere like scattered seeds.

Operation Mindfuck includes: Anti-Protests, Book OM or BookGASM, Culture Jamming, Erister Egg Hunt or EggGASM, Flash Mobbing, Guerilla Communication, Honorary Membership (in non-existent groups), OM Parades (odd and unexpected parades), Postergasm, Project Pan-Pontification, stamping official documents with unofficial Rubber Stamps, Project Jake, and more.
Let's donate some books to the jail where your uncle's locked up and sneak in "Principia Discordia". Give him some ideas for his own Operation Mindfuck on the guards.
Operation Mindfuck by Dildorgasm January 29, 2009

Manafucked

When you're at an incredibly great advantage (such as being wealthy, connected, or mana-full) but can do jack shit with it because an opponent renders your advantage meaningless.
*Paul Manafort gets his accounts frozen and co-conspirators indicted because he didn't know about the secret wire-tapping.*

NEWSPAPER HEADLINE: Mueller Manafucked Manafort