Lol-syndrome Share definition Flag When someone types 'lol' too many times in a conversation, they are then diagnosed with 'lol-syndrome'. 'loooooooooooooooooool' 'Dude, you got lol-syndrome.' 'loooool' '-_-' Lol-syndrome by TheBirdWithBlueEyes September 18, 2011 0 0 Get merch Get the Lol-syndrome mug. Buy Now — $32.95 See more merch