Lance Syndrome 

When a person decides to tell a love interest that they like them and get rejected, they become so depressed that instead of gaining weight they lose it.
(In honor of this kid who lost so much weight because he got rejected).

Pino: hey, have you noticed that Juan has lost a lot of weight?

Eddy: Oh, you didn't know? he suffered from Lance Syndrome. Some chick rejected him.

Lance Syndrome by Eddykid February 24, 2009

Lance Syndrome 

Refers to being an inbred liptard with down syndrome. Sadly, this is a lifetime disease. This disease is only associated with people named " Lance ".

Hey look at that guy! He's got that Lance Syndrome.

Lance Syndrome by InbredBreeder September 15, 2023