Guido Calhoun Share definition Flag A slur for a person of both Irish and Italian descent. "Yo, where'd Patty and Gina go?" "They're in the bathroom, making little Guido Calhouns." Guido Calhoun by Imbnd July 25, 2007 0 0 Get merch Get the Guido Calhoun mug. Buy Now — $32.95 See more merch
