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Game over, man! 

Usually a screen after a game is over due to loss of all lives or failing a critical objective, especially in older (video) games.

It is conceding defeat, in this instance. Bill Paxton's Private Hudson famously says this line in ALIENS, after the drop ship coming to rescue him and his expedition crew crashes.
Private Hudson : (after the drop ship crash) Well, that's great. That's just fuckin' great, man! Now what the fuck are we supposed to do? We're in some real pretty shit now, man!

Corporal Hicks : (grabs him by the shirt) Are you finished?

Newt : I guess we're not gonna be leaving now, right?

Ripley : I'm sorry, Newt.

Newt : You don't have to be sorry. It wasn't your fault.

Private Hudson : That's it, man. Game over, man! Game over! What the fuck are we gonna do now? What are we gonna do?
Game over, man! by bimn May 5, 2019

Game Over, man! Game Over! 

What Hudson (The Ultimate Bad Ass) says after his Squads Evac Drop ship is taken down by the Xenomorphs. Spoken when your plan for an important mission fails horribly and then you end up pretty much boned.
Shit! I was going to bake some home made cookies but all I have is raisins.

Game over, man! Game over!
well known from south park
rednecks get angrry that future folk took there jobs so they yell
They took ouare jerbs!
Them future folk took ouare jerbs!
jerb by Jimberley Kim April 7, 2005
Word of the Day on May 22, 2026
An Irish phrase meaning shit, derived from ass
(Not to be confused with the literal description of one's buttocks)
"Did you hear the song Aylek$ dropped?"
"Hardly. Her music is absolute cheeks."

"My boyfriend say LaFlame is cheeks."
"Tell your boyfriend I said it's his mixtape that's cheeks."
Cheeks by thecartisan April 26, 2020
Word of the Day on May 21, 2026

sans sheriff 

Lawless use of fonts or typography, with no regard to aesthetics or legibility
I'm putting this CV straight in the bin. Written totally sans sheriff.
sans sheriff by Jamarley July 3, 2019
Word of the Day on May 20, 2026

Breadhead 

Someone who is addicted to obtaining money and building wealth. A money addict and fanatic. Breadheads often work more than one full-time job, and some even participate in illicit activities to "obtain the bread".
A breadhead is like a crackhead, but for money instead of crack.
Breadhead by 🅱️ U S 3 4 8 March 30, 2022
Word of the Day on May 19, 2026