fuck muffin Share definition Flag N. An affection term, normally said by the guy to the girl. Origin: Joe Joe: Bye fuck muffin, love u lots! Jen: Bye cup cake, see u later on tonight! ;-) fuck muffin by Jen July 29, 2004 0 0 Get merch Get the fuck muffin mug. Buy Now — $32.95 See more merch