An area in Southern Colorado known for its farming, gangs, cannabis production, and supernatural & alien activity. See also: San Luis Valley
Hey, we boutta hit up the Fertile Crescent to see some crop circles. Wanna come?

Man, you KNOW those Fertile Crescent strains are the best!

Those farmers in the Fertile Crescent be trippin, man. Cannabis so good that the aliens come to get it.
by Kensco7 November 6, 2018
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A vagina, usually a peach that is unfortunately baby prone.
Nine months ago I planted my schlong in Rachel's fertile crescent, and now with child support I'll be paying for it over the next 18 years.
by Goody1 November 15, 2007
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The region of America (generally mid-western states such as Ohio and Wisconsin) where super fertile women exist. They can generally pump out several babies a year, employing them as field hands and have quick 'snap backs.'
Judgy Asshole: It was super irresponsible for you to conceive another kid, you can barely take care of yourself!

You: I'm from the American Fertile Crescent. That guy only fingered me and I got pregnant!
by Fitty Fishy July 5, 2022
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