An area in Southern Colorado known for its farming, gangs, cannabis production, and supernatural & alien activity. See also: San Luis Valley
Hey, we boutta hit up the Fertile Crescent to see some crop circles. Wanna come?

Man, you KNOW those Fertile Crescent strains are the best!

Those farmers in the Fertile Crescent be trippin, man. Cannabis so good that the aliens come to get it.
by Kensco7 November 06, 2018
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A vagina, usually a peach that is unfortunately baby prone.
Nine months ago I planted my schlong in Rachel's fertile crescent, and now with child support I'll be paying for it over the next 18 years.
by Goody1 November 15, 2007
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