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Mrs Dubose was the evil old women from the Harper Lee novel, To Kill a Mockingbird.

Dubose - an adjective to describe something or someone as bitter, evil or harsh
1)
1st person: 'Shit, that litrature teacher is Dubose'

2nd person: I know, that Dubose bastard gave us fuck loads of word
Dubose by Willma Shambles March 22, 2009
Related Words
A person who often has flea bites or tends to scratch there balls alot.

To live with fleas on balls.
My dog is dubosed right now!
Dubose by Jasper Lunger November 12, 2009

Dubose middle 

Dubose is full of preps and criminals. it’s one of “The best district”. they have fights,cops,weave all over the place.
girl 1: “I’m going to dubose middle school
boy: “there’s cops and weave. be careful
Dubose middle by looolitsmeee September 9, 2021

Brandon Dubose 

Thor? Yea he's Brandon Dubose's bitch. I once saw a Brandon Dubose rip a 14ft tall grizzly bear in half and later use it as a rug. I once thought a Brandon Dubose was riding a horse into battle, it was just a wheelbarrow full of his balls. Bitches beware, your clit has no chance against a Brandon Dubose.
Who the hell made this mess?

Brandon Dubose
Brandon Dubose by Purpl3nurpl3 November 19, 2015

brandon dubose 

is a term for a lazy slacker that cant rap for his life and has the lowest respect for women and constantly acts like a kid
White Plains, New York.
The home town of the biggest ballers on the East Coast.
Boy one: Yo that guy's so chill!

Boy two: Yeah that's because he's from Dubset