Mad scientist archenemy of the superhero Spider-Man; originated in Amazing Spider-Man #3. Named because his powers consist of four robotic tentacle-like arms, which were welded to his body in a laboratory accident. Played by actor Alfred Molina in the second Spider-Man movie. A much better supervillain than Venom, in my opinion.
Dr. Otto Octavius. A nuclear scientist and skilled inventor, he created a set of four robotic tentacles that were controlled with a neural interface. After a lab accident welded them to his body, he suffered brain damage and became a mad megalomaniac- and arguably the biggest headache for Spider-Man.