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It means "Down To Fortnite"
D.T.F by YeBoiCheese September 24, 2020
Down to Fortnite
Hey, man are you D.T.F tonight.
D.T.F by THEtrafficC0NE September 24, 2020
down to fuck

trying to hook up, and/or have sex.
drunk stephen: yo boo, d.t.f.?
random girl: d.t.f.?
drunk stephen: yeah boo, you down to fuck?
d.t.f. by stephen wainwright March 20, 2008
means: Down To Fuck

used in superbad
"dude, im gonna get laid! shes D-T-F!"
D-T-F by oisuxx October 23, 2007
Acronym for "down to fuck."
All the hoes in this party are D.T.F.
D.T.F. by E.S.M. January 14, 2008

D..T..F.. 

Hey are you D..T..F.. Mcdonalds closes at 12.
D..T..F.. by Cuddy2000 March 17, 2021