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Cross Threaded 

When you are taking a crap, and it takes you a long time, and it feels as if a boulder is being squeezed from your ass. It hurts and feels like it's coming out sideways.
You go back to your desk and someone says "dude you were in there a long time", you respond by saying "dude, i had one cross threaded"
Cross Threaded by Jamhole September 29, 2005

Cross Threader 

Male who has sexual intercourse with both males and females.

To insert "Thread" you're penis in both male and female.
A bi-sexual male would be a cross threader.
Cross Threader by pornicus March 21, 2013

Crossthreaded 

Crossthreaded. Mad .upset. pissed off
I don't know what you did but boy is she crossthreaded
Crossthreaded by anonymous July 6, 2021