When something becomes completely destroyed, usually beyond repair, or possibly to the point where repairs would cost more than the value of whatever became destroyed.
Vulgar Slang Verb
Past tense: fucked, Screwed over, Screwed up, Fucked up beyond recognition, Fucking has really been fucked up to the point of it's highest high archery!!!
To be looked at by your peers as a completemushmellow when you cannot complete the simplest of chores in your profession. You are laughed at because while trying to complete these tasks your hands shake and lips quiver.
Pretty sure that guy felt frenzeled because of having to do his job. Did you see him he must have been shaking like that because O Dog gave him a reach around in the chocolatemeat locker.