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cobra= lashing out poisonous mammal, ambushful and unpredictable.

oprah= powerful female.

cobra + oprah = a powerful poisonous female mammal that lashes out on contact.

synonymous with "bitch" , "crazy woman", or " your mother in law"
As in

"boy don't make me go cobra oprah on yo ass!!!"

"ooooooo babyyy, that girl got some cobra oprah in her step, mmmmmmhmmm make a grown man cry"

"I left that bitch tomorrow she too cobra oprah fo me, ya on level?"
by couturegirl08 April 11, 2010
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Oct 31 Word of the Day
1. acronym for Laugh Out Loud + sob -- an expression for something that makes you lol and cry at the same time.

2. acronym for Laugh Out Loud, Son of a Bitch. An expression of bitter anger over something funny.
That fatal clown car accident made me lolsob-- clown cars are funny but my best friend was driving.
by duenna9 October 12, 2009
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