Chortlephins Share definition Flag Noun, the chemical you release when you chortle. Closely related to the endorphin family. To laugh is to release Chortlephins. "I just saw a bloke fall over in the street, boy did i release chortlephins!" Chortlephins by Hollifer February 5, 2010 0 0 Get merch Get the Chortlephins mug. Buy Now — $32.95 See more merch