Top definition
A replacement noun for any of the various food products ending with "O's" that contain a large amount of unhealthy qualities, or any other spherical foodstuffs such as donuts, cookies, etc.
"Hey mother, what are you making for dinner tonight?"

"Well, I was considering conjuring up some onion rings as an appetizer, some spaghetti o's for the main course, and some donuts and Oreo's for dessert."

"Yeah right, why don't we throw in some Cholester O's while we're at it."

"That's a great idea!"
by Loch Raven November 28, 2009
Get the mug
Get a Cholester O's mug for your Uncle Callisto.