B.I.G (Bitch Is Gone!) Share definition Flag Bitch Is Gone! Acronym signifying the end of a realtionship or marriage to a complete Bitch. I'm glad B.I.G (Bitch Is Gone!) B.I.G (Bitch Is Gone!) by JERKER19 July 18, 2010 0 0 Get merch Get the B.I.G (Bitch Is Gone!) mug. Buy Now — $32.95 See more merch