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Ope is the Midwestern way of acknowledging another person or thing that they have encountered.
Ope! Sorry I bumped into you Jim.

Ope, there's my wallet.

Ope! I missed my bus!
Ope by Pandar937 May 24, 2018
Related Words

Oprah Effect 

The almost viral phenomenon that occurs when Oprah endorses a cause or person or product. When Oprah announces her approval of something, its popularity will almost surely escalate to the point of frenzy.
First introduced by the cable news networks' 2008 Presidential election campaign coverage.
Woman # 1: "Did you hear that Oprah's backing Barack Obama for president in '08?"
Woman #2: "I'm voting for him. He's got the Oprah Effect."

Man # 1: "Now, how in the hell did Dr. Phil get his own show?"
Man # 2: "Must be the Oprah Effect, man."
Oprah Effect by terribleDH January 10, 2008
Being under the influence of an opiate based substance (Opium, Heroin, Oxycontin, Morphine, Hydrocodone)
Example 1: After getting a dose of morphine in the ambulance Miles felt opiated.

Example 2: "I was so opiated last night after popping some oxycontin"
Opiated by MilesGraham November 4, 2011

Optical Iboobsion 

When you see a bitty on a semi-consistent basis and you don't think her rack is up to snuff then BAM! bikini pics upload to the fb and you realize she has some cannons.
Friend 1: Her boobs are not that nice.
Friend 2: They are too. It is an optical iboobsion

Operation Couch Potato

The process of trying to convince your lazy ass friend to go out and hang out with people.
"This guy would rather sit next to his computer and play video games rather than go to Michelle's party. I'm going Operation Couch Potato on him."

Operating Engineer 

Bascially a professional badass, the Liam Neson's of the engineering world. These guys do the shit you can't, fix the shit you can't, and run the shit you can't. Typically paid over 100,000 a year, these are the people that keep your world running.
Oh you're an operating engineer, well I won't be needing these pants anymore.