1. to adjust slightly

2. to adjust a computer program slightly
They tweaked the game to fix a glitch.
by Light Joker August 26, 2007
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v- to tweak
to be extra twitchy, secretive, giggly while under the influence of weed, pot, marijuana
to have the tell-tale signs of being high (squinty eyes, blood-shot eyes)
"Yo after taking those five rips off the bong, I was totally tweaking out. I was pulling my hoodie all the way down, I put sunglasses on, and my eyes were BARELY open"
by bnell9002 November 11, 2005
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To adjust or fine tune things, to personalise an object and make it better to suit one's liking
Holly was eager to tweak her sister's white canvas slip-ons with rainbow unicorns because she knew they were her sister's favourite mythical creatures.
by fln September 23, 2013
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Computers: To slghtly alter various settings and configurations for customisation and improving performance.
You can get better framerates in the game if you tweak some settings.
by generic January 21, 2004
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Using your index and middle finger to squeeze someone's nipple; "the power of two becoming one"; can add "power" as a prefix to denote hard or rough; can indicate holidays (e.g., Merry Tweaksmas; Happy Tweaksgiving; St. Patweak's Day)
"It's time for your tweaking--give up those tender nipple buds!"
"We wish you a Merry Tweaksmas and a Happy New Tweak Year!"
"Okay, you can tweak me, but no power tweaks. Got it?"
by Freak Nastay February 25, 2003
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1. Become influenced by drugs or Foreign substances...in a bad way

2. IT. To say you fixed something on a PC or Server when you really broke it, and really broke it goood.
1. maaaan... I'm so tweaked out, I vomited all over myself while driving on the Motrway

2. IT. Tim Black the ginga...grrr
by Bob is u're auntie August 23, 2008
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An idea that just appeared. When your mind brings a solution to something into your thoughts.
In a conversation with someone you are trying to pick out a solution to a maths sequence and suddenly your brain recoginses the pattern........you tweaked to the idea being used.
by Mr Berry, Moon March 14, 2012
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