Dude, all I said was "hi" and he started tweakin'! What's his deal?
by Anonymous April 19, 2003
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1. Customise or modify (something) to suit a particular individual or task
2. Improve (a mechanism or system) by making fine adjustments to it

synonyms: adjustment, modification, alteration, change, adapt, customise
I am going to tweak the design a little more on photoshop
by eslupmaet June 16, 2014
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To space out intensely while under the influence of some sort of psychotropic drug.
Guy 1: *spacing out, drooling*
Guy 2: what's wrong with you?
Guy 1: huh?
Guy 2: Dude you're tweaking.
by Fishmanist January 9, 2010
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It's YOUR brand, do what ya' gotta do!
Dude, I helped TWEAK design a shoe!

The TWEAK Rhett & Link Mythical Shoes are the coolest shoes ever check them out!
by TWEAKfootwear April 4, 2011
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To give a girl's clit a real workout, I mean, like when you give it the rub-a-dub taking it between your thumb and index. Not to be confused with mere twiddle.
I was giving her a real tweaking when her mother walked in on us.
by Hugh G Rection October 7, 2003
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