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Sublime lead singer Brad Nowell's dog
It smelled like Lou Dog inside the van
Lou dog by AceRockola April 9, 2005
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Lou M. Taylor 

The CEO of Tri Star Sports & Entertainment. A money hungry, fake religious, shady, business manager who loves to trap Hollywood starlets into conservatorships in order to steal their money & drain their assets into foreign countries. Has stolen at least 600 million from Britney Spears fortune.
Lou M. Taylor, once tried to perform an exorcism on me because I was gay.
Lou M. Taylor by FREEBRITNEY4EVER1 October 16, 2021

Lou Reed 

A rock 'n' roll songwriter and performer who had Urban Dictionary pegged before it existed. Some of the same factors that made UD what it is may also have led Reed into self-destructive substance abuse at one phase of his career.
"And everybody puttin' everybody else down"
-- Lou Reed, "Heroin"
Lou Reed by Leslie Doppler October 1, 2008
smart, funny, always looking to help. A person that can be counted on and you can count on keeping your secrets. As a child - curious. As an adult - everyone's rock. As a mother - a reliable and consistent. Always "the best mom" in the neighborhood even though all the kids now the homework MUST be done first. She has more love to give than those who are willing to cherish it. She is not always right nor is she always the best at everything but you always know she gives you her best.
I wish I had a Lou Ann in my life. I wish I had a Lou Ann for a mom.
Lou Ann by Easternsky August 31, 2010

Lou Ferrigno is right 

Used at the beginning of a sentence to lend star credibility to whatever is about to be said.
Lou Ferrigno is right, I look really good in orange.

Lou-blue 

Louis tomlinson's eye color. aka the exact shade of blue Harry Styles wanted to wear and the walls to be in the Lights Up music video
Everything in the Lights Up music video is Lou-blue.
Lou-blue by Tonniey October 15, 2020